Association of parental FEF25-75% during a methacholine challenge and children's PC20 and diagnosis of asthma
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چکیده
منابع مشابه
Association of parental FEF25-75% during a methacholine challenge and children's PC20 and diagnosis of asthma
Background There is evidence that paternal and maternal lung function influence children’s pulmonary function. To date, the most widely used pulmonary function test (PFT) to assess airway responsiveness is the PC20 (concentration of methacholine required to decrease FEV1 by 20%). However, other measures of parental lung function may be better predictors of airway responsiveness or asthma develo...
متن کاملRole of Methacholine PC20 in FEF25-75% for the Diagnosis of Bronchial Asthma
Background: The methacholine bronchial provocation test is a useful tool for evaluating asthma in patients with normal or near normal baseline lung function. However, the sensitivity of this test is 82∼92% at most. The purpose of this study is to evaluate the clinical usefulness of FEF25-75% in identification of airway hyperresponsiveness in patients with suspected asthmatic symptoms. Methods: ...
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15 صفحه اولCirculating microRNAs and association with methacholine PC20 in the Childhood Asthma Management Program (CAMP) cohort
INTRODUCTION Circulating microRNAs (miRNA) are promising biomarkers for human diseases. Our study hypothesizes that circulating miRNA would reveal candidate biomarkers related to airway hyperresponsiveness (AHR) and provide biologic insights into asthma epigenetic influences. METHODS Serum samples obtained at randomization for 160 children in the Childhood Asthma Management Program were profi...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Clinical Immunology
سال: 2010
ISSN: 1710-1492
DOI: 10.1186/1710-1492-6-s3-p32